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Macular changes with optic coherence tomography (OCT) in patients with Alport syndrome

Session Details

Session Title: Imaging II

Session Date/Time: Sunday 29/09/2013 | 08:00-10:00

Paper Time: 09:12

Venue: Hall G1 (Level 2)

First Author: G.Yilmaz TURKEY

Co Author(s):    G. Gokgoz   E. Yaman Pinarci   S. Akca Bayar   A. Cetinkaya     

Abstract Details


To evaluate the macular changes with optic coherence tomography (OCT) in patients with Alport Syndrome.


Baskent University, School of Medicine, Department of Ophthalmology


20 eyes of 10 patients with the diagnosis of Alport Syndrome, and 20 eyes of healthy patients who were recruited in this cross-sectional and comparative study. After a complete ocular examination, macula was evaluated in nine retinal sections by SD-OCT.


The mean foveal, temporal and nasal thickness of the Alport retinas were 239±37µ, 259±20µ, and 322±36µ respectively. In the control group these measurements were 252±22µ, 314±14µ, and 325±12µ, consecutively. Decreased temporal thickness of the retina was statisticaly significant (p:0.006). The thinning of the whole retina was principally due to thinning of the ILM/nerve fiber layer and inner nuclear layer.


Retinal thinning in the temporal area with SD-OCT imaging in Alport syndrome may be a characteristic finding.

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