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What is the risk of neuronal complications of intravitreal silicone oil?

Session Details

Session Title: Quick Fire Free Paper Session 03

Session Date/Time: Sunday 29/09/2013 | 08:30-09:30

Paper Time: 08:25

Venue: Hall C (Level 1)

First Author: A.Grzybowski POLAND

Co Author(s):    J. Pieczynski   J. Ascaso           

Abstract Details


This study summarizes our current understanding of the specific pathogenic mechanisms of intraocular SiO neuronal side effects and estimates the risk factors associated with this complication.


Analysis of all published papers on the subject.


We used Pub Med web platform to search for neuronal complications of intravitreal silicone oil over a period of 25 years. We have searched for prospective or retrospective studies and case reports.


Intracranial migration of the SiO through the optic nerve posterior to the lamina cribrosa to the optic chiasm and brain is uncommon. The mechanism is still under debate, but it has been suggested elevated intraocular pressure or/and optic nerve head anatomical predispositions as potential explanations.


The risk of the extraocular SiO penetration, in the absence of preexisting glaucoma or optic nerve abnormalities, is so low, that the use of SiO endotamponade in complex retinal detachment patients does not need to be modified. It is postulated that patients with optic nerve abnormalities and glaucoma should be monitored by MRI images to assess extraocular SiO migration.

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