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The frequency and terms the decreasing of retinal nerve fiber layer thickness in patients with uveitis complicated by optic neuritis

Session Details

Session Title: Uveitis & Intraocular Tumours

Session Date/Time: Friday 27/09/2013 | 14:30-16:00

Paper Time: 15:10

Venue: Hall C (Level 1)

First Author: M.Panchenko UKRAINE

Co Author(s):    M. Samofalova   O. Honchar   S. Halimonenko        

Abstract Details

Purpose:

To investigate the frequency and terms of the retinal nerve fiber layer (RNFL) thickness in patients with uveitis complicated by optic neuritis.

Setting:

Kharkiv National Medical University, Ukraine

Methods:

The study included 32 patients (41 eyes) with uveitis complicated by optic neuritis, aged between 16 and 71 years.

Results:

The decrease of retinal nerve fiber layer thickness was defined with significant decrease of it’s mean thickness, according to optical coherence tomography (in obedience to Mwanza J.C., 2010). After the relief of the inflammatory process in the uvea and reduce of the optic disc swelling, sector RNFL thickness was observed in 75.6% of eyes. The initial degree of RNFL thickness was observed in 43.9% of eyes, the moderate degree - in 24.3% of eyes, the manifest degree - in 9.7% of cases. The signs of decreasing RNFL thickness were observed in the period of 3 months in 46.3% of eyes. The decreasing of RNFL thickness was formed in 5-6 months after inflammatory process in 14.6%. Most eye patients with anterior uveitis complicated by optic neuritis the decreasing of RNFL thickness formed in a period of 3 months. In the eyes with posterior uveitis, the decreasing of RNFL thickness formed in a period of more than 3 months.

Conclusions:

The decreasing of RNFL thickness were observed in 75.6% eyes of patients with uveitis complicated by optic neuritis after inflammation was determined .The decrease of RNFL thickness were formed in the first 6 months in most cases (60.9%) after uveitis complicated by optic neuritis.

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