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Analysis of Kyrieleis plaques by spectral domain optical coherence tomography images

Session Details

Session Title: Uveitis & Intraocular Tumours

Session Date/Time: Friday 27/09/2013 | 14:30-16:00

Paper Time: 14:54

Venue: Hall C (Level 1)

First Author: R.Dolz-Marco SPAIN

Co Author(s):    R. Gallego-Pinazo   S. Mrejen   P. Hern?ndez-Mart?nez   J. Giovinazzo     

Abstract Details


To report the spectral domain optical coherence tomography (SD-OCT) characteristics of Kyrieleis plaques (KP).


University and Polytechnic Hospital La Fe, Valencia, Spain.


The ophthalmic charts of all cases with KP were reviewed in this study. The dilated fundus examination (DFE), fluorescein angiography and SD-OCT images were analyzed.


Six patients (2 males; 4 females) were included. The etiology of the intraocular inflammation preceding KP development were: toxoplamosis (3), sarcoidosis (1), sterile endophtalmitis (1) and acute retinal necrosis (1). Two different patterns were identified: on the one hand, 4 cases showed round yellowish-white segmented plaques overlying both retinal arteries and veins in a beaded pattern that where evidenced in the SD-OCT images as hyper-reflective round lesions over the inner retinal surface aligned with the vessels and surrounding their walls; on the other hand, 2 cases showed a continuous periarterial-only whitening demonstrated in the SD-OCT images as an increased linear hyper-reflective arterial walls.


The exact location of KP is still controversial as there has not been reported yet any hystopathological correlation. The cases we report evidenced two different patterns previously undescribed. We warrant further studies to assess the clinical relevance of these findings.

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