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Long-term effect of infliximab treatment for Bechet's uveitis

Session Details

Session Title: Uveitis & Intraocular Tumours

Session Date/Time: Friday 27/09/2013 | 14:30-16:00

Paper Time: 14:38

Venue: Hall C (Level 1)

First Author: K.Nakai JAPAN

Co Author(s):    K. Nishida              

Abstract Details


To evaluate the long-term effect of infliximab (IFX) for treating Bechet's uveitis.


Retrospective review of 24 patients treated with IFX and followed 24 months (M).


The inflammation was scored 0-3 6 M before and every 6 M after IFX. Patients were divided in two groups (one with long-term efficacy and the other with lost response), based on the score. The C-reactive protein (CRP) level was measured.


Seven patients had a lost response (scores: 6.3 before IFX; 1.4, 0-6 M after IFX; 2.1, 6-12 M; 2.7 12-18 M). Seventeen patients had long-term efficacy (scores: 3.8, 0.3, 0.1 and 0.1, respectively); the scores was significantly lower (P<.05) even before IFX, with no significant difference in CRP.


Patients with high inflammation scores before IFX should be observed carefully.

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