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Multi-spot single-session vs single-spot multiple-session panretinal photocoagulation in proliferative diabetic retinopathy- our experience

Session Details

Session Title: Vitreoretinal Surgery I

Session Date/Time: Thursday 26/09/2013 | 11:00-12:30

Paper Time: 11:40

Venue: Hall 3 (Level 0)

First Author: S.Mokadam INDIA

Co Author(s):    M. Joglekar              

Abstract Details


To evaluate the effects of pattern laser (Visulas 532s VITE system (Carl Zeiss, Germany)) multispot panretinal photocoagulation given in a single session (SS-PRP) vs single-spot multiple-session PRP (MS-PRP) on proliferative diabetic retinopathy (PDR).


Anjani Eye Hospital, Nagpur, India.


Single-center, randomized clinical trial of 100 eyes. Proliferative diabetic retinopathy was treated with a 200-micron spot size in 2400 burns given either as Pattern laser with VITE in 40-millisecond SS-PRP or in 3 sessions as 150- millisecond MS-PRP, during a 3-week period. Central subfield retinal thickness (CRT) was recorded at baseline and 4 and 12 weeks. Clinical regression of retinopathy and patient comfort, as to repeated visits and pupil dilatation, were noted.


There was a significant increase in mean CRT with MS-PRP (22 μm at 4 weeks, 20 μm at 12 weeks) as compared to no significant increase in the SS-PRP group. Similarly the mean macular volume also showed an increase in the MS-PRP group. At 12 weeks, clinical regression of the PDR was equal in both groups. As regards to patient comfort, all the patients, except one preferred SS-PRP, if given a choice for their PRP.


Even though both, the multi-spot SS-PRP and the single-spot MS-PRP, are equally efficient in clinical regression of the PDR, SS-PRP doesn’t have increase in the CRT or macular volumes as noted on SD-OCT, and so is safer compared to MS-PRP. The SS-PRP reduces the number of patient visits and in turn is comforting to the patient, saving his/her time and money.

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