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Isolated and pedicled graft in choroidal RPE patch transplantation

Session Details

Session Title: Vitreoretinal Surgery I

Session Date/Time: Thursday 26/09/2013 | 11:00-12:30

Paper Time: 11:16

Venue: Hall 3 (Level 0)

First Author: M.Stopa POLAND

Co Author(s):    P. Rakowicz              

Abstract Details

Purpose:

to report results of pedicled and isolated autologous choroidal RPE patch transplantation surgery for treatment of submacular hemorrhage in a patients with age related macular degeneration.

Setting:

a retrospective case series of 5 patients (3 males and 2 females) report with a follow of 4 to 40 months.

Methods:

All patients experienced sudden vision deterioration due to submacular hemorrhage in AMD. They were treated with autologous choroidal RPE patch transplantation. The surgery involved a 180° degree peripheral retinectomy and the preparation of an RPE choroid graft (pedicled grafts in 2 eyes and isolated grafts in 3 cases). Outcome measures included preoperative and postoperative visual acuity at 1, 3 months and at the end of the follow up as well macular status on postoperative OCT scans.

Results:

It was feasible to remove submacular hemorrhage and CNV and prepare choroid RPE graft in all eyes. A severe postoperative hemorrhage that lead to vision deterioration was observed in one eye. In one other case a retinal detachment occured that was treated with successive vitrectomy. Visual acuity improved in 4 patients and remained stable in 1 case. The perfusion of the graft was confirmed in ICG angiography.

Conclusions:

Surgical techniques for preparation of pedicled and isolated grafts seem to present comparable challenge. Both strategies of autologous choroidal RPE patch transplantation are a surgical option for submacular hemorrhage treatment in AMD.

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