Session Title: Imaging I
Session Date/Time: Thursday 26/09/2013 | 08:30-10:30
Paper Time: 09:02
Venue: Hall 3 (Level 0)
First Author: A.Ellabban JAPAN
Co Author(s): A. Tsujikawa S. Ooto K. Yamashiro A. Oishi
To study the prevalence and three-dimensional (3D) tomographic features of focal choroidal excavations (FCE) in eyes with central serous chorioretinopathy (CSC) using swept-source optical coherence tomography (OCT).
Prospective cross-sectional study. This study was conducted in the department of ophthalmology and visual sciences, Kyoto University hospital, Japan.
We prospectively examined 116 consecutive eyes with CSC with a prototype 3D swept-source OCT at 1,050 nm. 3D images of the shape of the macular area, covering 6 x 6 mm3, were reconstructed by segmentation of the outer surface of the retinal pigment epithelium (RPE).
3D swept-source OCT detected FCE in 9 eyes (7.8 %). The 3D scanning protocol allowed for detection of small extrafoveal excavations and the 3D segmentation method coupled with en-face scans allowed for clear visualization of the morphology of the excavations. In 5 eyes with FCE, unusual choroidal tissue was detected beneath the FCE, bridging between the bottom of FCE and the outer choroidal boundary. In addition, three of those five eyes showed a suprachoroidal space below the FCE, as if the outer boundary of choroid is pulled inward by this bridging tissue. FCE was often seen within the leakage point and choroidal hyperpermeability. Eyes with FCE were more myopic (-4.42 ± 2.92 diopters), and the subfoveal choroidal thickness was significantly thinner (301.3 ± 60.1 µm), as compared to control CSC eyes (P = .001 and .036 respectively).
FCE is present in approximately 7.8% of eye with CSC. In eyes with CSC, FCE could be formed by the retraction of the RPE by the focal scaring of the choroidal connective tissue.