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Assessment of retinal nerve fiber layer in pseudoexfoliation syndrome

Session Details

Session Title: Quick Fire Free Paper Session 01

Session Date/Time: Thursday 26/09/2013 | 08:30-10:30

Paper Time: 10:20

Venue: Hall G1 (Level 2)

First Author: E.Cetin TURKEY

Co Author(s):    S. Acer   A. Cevik   G. Pekel   A. Ka??kc?     

Abstract Details

Purpose:

To assess the peripapillary retinal nerve fiber layer (RNFL) and central macular retinal thickness (CMT) in patients with pseudoexfoliation syndrome (PXS)

Setting:

Pamukkale University, Department of Ophthalmology, Denizli, Turkey

Methods:

The patients who were diagnosed as PXS without glaucoma were included in this prospective study. Age and gender matched subjects without PXS comprised the control group. The patients with diseases that may affect RNFL and macula or prevent optimum imaging were excluded. Peripapillary RNFL and CMT were measured by optical coherence tomography (Heidelberg Engineering GmbH, Heidelberg, Germany). Peripapillary RNFL and CMT were compared between the study group and the control group.

Results:

PXS group was consisted of 23 patients with a mean age of 67.7±9.5 whereas the control group was consisted of 32 patients with a mean age of 64.0±9.9 (p=0.170). The groups were well balanced in terms of gender (p=0.187). The mean CMT, mean peripapillary RNFL, nasal RNFL, superior nasal RNFL, superior temporal RNFL, inferior nasal RNFL, inferior temporal RNFL and temporal RNFL were 264.6±17.1, 94.0±12.2, 82.9±22.2, 105.2±18.8, 125.8±22.1, 104.8±19.9, 129.4±25.1, 65.3±13.0 in the PXS group whereas they were 264.7±18.4, 103.6±10.0, 84.1±22.6, 109.8±25.3, 137.6±20.1, 123.8±24.8, 146.8±28.4, 71.2±12.4 in the control group respectively (p=0.995, p=0.002, p= 0.848, p=0.456, p=0.039, p=0.003, p=0.02, p=0.084). The mean peripapillary RNFL, superior temporal, inferior temporal and inferior nasal RNFL were significantly thinner in PXS group than that in the control group.

Conclusions:

There was a significant thinning in peripapillary RNFL in eyes with PXS without glaucoma compared to controls.

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