Effectiveness of Ultrathin 40-gauge Needle for Intravitreal Injections

Poster Details

First Author: Y.Ji SOUTH KOREA

Co Author(s):    J. Jang                             

Abstract Details


To report the effectiveness of ultrathin 40-gauge needle for intravitreal injections.


Chonnam National University Hospital, Gwangju, South Korea


A total of 50 patients were included. 45 Patients received 2 consecutive intravitreal injections with both a 30-gauge and a 40-gauge needle in randomized order, and 5 patients had simultaneous injections in their both eyes with different needles. After each injection, patients were asked to grade the injection-related pain using the visual analogue scale (VAS). Subconjunctival haemhorrage and vitreous reflux were graded by the amount or conjunctival bleb size (grade 0 – 4).


The 40-gauge needle resulted in lower VAS pain scores (2.40 vs 3.92, P<0.001) and vitreous reflux (0.31 vs 2.26, P<0.001) compared with 30-gauge needle. There was no significant difference in the subconjunctival haemhorrage (0.63 vs 0.67, P=0.69).


The use of an ultrathin 40-gauge needle for intravitreal injections showed significant effects in reducing the pain and vitreous reflux compared with the use of a 30-gauge needle.

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