Posters

Retinal microstructures and sensitivity after vitrectomy and internal limiting membrane peeling for epiretinal membrane: Evaluation using swept source optical coherence tomography and humphrey 10-2 program

Poster Details

First Author: H.Terashima JAPAN

Co Author(s):    H. Hasebe   N. Matsuoka   T. Togano   T. Fukuchi                    

Abstract Details



Purpose:

To use swept source optical coherence tomography (SS-OCT) and Humphrey 10-2 program (HFA10-2) to evaluate the retinal microstructures and sensitivity after vitrectomy with internal limiting membrane (ILM) peeling for epiretinal membrane (ERM).

Setting:

retrospective, non-randomized study

Methods:

The study included 34 treated eyes in 34 patients with ERM who underwent 25gauge vitrectomy with ILM peeling. We examined retinal sensitivity using HFA10-2 and ganglion cell complex (GCC) thickness with SS-OCT before and 3 months after vitrectomy (the ERM eye and healthy fellow eye: control eye). The GCC thickness and macular sensitivity were analyzed using the standard early treatment of diabetic retinopathy study (ETDRS) grid, and the 68 points of measured thresholds using HFA10-2 were allocated to the corresponding location of the ETDRS grid. The retinal microstructures and sensitivity were compared between baseline and 3 months after vitrectomy.

Results:

At baseline, the mean macular sensitivity in ERM eyes was significantly lower than that in the control eyes (p<0.001). While the mean change in the macular sensitivity was not significantly different between before and after vitrectomy at 3months (p=0.055), whatever outer superior, outer nasal and inner nasal sensitivity were significantly lower after vitrectomy (p=0.022, p=0.011 and p<0.001, respectively). The mean macular GCC thickness after vitrectomy was significantly thicker than that in the control eyes (p=0.03), whereas outer temporal GCC thickness was significantly thinner (p=0.03). Postoperative the mean macular sensitivity significantly correlated with GCC thickness (p=0.003, r=-0.547).

Conclusions:

The combination analysis of HFA10-2 and SS-OCT using ETDRS grid is effective to evaluate the postoperative retinal function and microstructures.

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