Posters

Alterations in Bruch's membrane and retinal pigment epithelium in pigmented small choroidal tumors observed in swept source OCT

Poster Details

First Author: D.Pelayes ARGENTINA

Co Author(s):    A. Folgar   J. Zarate   D. Buonsanti   I. Ibarra                    

Abstract Details



Purpose:

In pigmented small choroidal tumors, complex retinal pigment epithelium - Bruch membrane has been considered a key point in the development and evaluation of these tumors, new technologies such as the SS-OCT allow us to study these areas with high resolution. We report 15 cases of these tumours studying the complex retinal pigment epithelium - Bruch membrane with SS-OCT.

Setting:

MOS Maimonides Ophthalmology School, Maimonides University, Buenos Aires, Argentina. Ophthalmological centre investigation and development (COID), Maimonides University, Buenos Aires, Argentina.

Methods:

We included 15 eyes of 15 patients with choroidal tumors small pigmented which we regard as (less than 3 mm in height and less than 10 mm base) to which underwent complete eye examination and imaging With swept-source OCT ( SS-OCT), fluorescein angiography, autofluorescence and ultrasonography. For SS-OCT, to scan acquisition protocol was used Involving 12, 6 and 3 mm horizontally and vertically scans in the posterior fundus. We classify Bruch's membrane as : 1- unchanged , 2- tuned or elongated, 3- microcracks , 4- break. ; and the pigment epithelium predominantly 1- hypotrophic , 2- atrophic , 3- hyperplastic , 4- unchanged. The follow-up was 18 months.

Results:

Patients in the study were 9 males and 6 females with an age range (39-72 years). We found in the observation that SS- OCT Bruch's membrane: 1- unchanged 0 patients (0%), 2- tuned or elongated: 9 patients (60%), 3- microcracks: 12 patients (80%), 4- break: 3 patient (20%); and the pigment epithelium as predominantly 1- hypotrophic: 3 patients (20%), 2- atrophic: 0 patients (0%), 3- hyperplastic: 9 patients (60%), 4- unchanged: 0 patients (0%) . In the 4 patients (27%) had growth and characteristics of malignancy of which we saw as elongation findings and / or microcracks of Bruch's membrane 4 patients (100%), combined disorders of the retinal pigment epithelium as predominantly hyperplasia 4 patients (100 %).

Conclusions:

We observed in our patient monitoring changes in the retinal pigment epithelium predominantly hyperplastic changes and in Bruch's membrane such as elongation and thinning microcracks had a was associated with growth and / or development of malignant lesions. New technologies such as the SS-OCT could provide data on clinical evaluation in these tumors are difficult to diagnose.

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