Alterations in Bruch's membrane and retinal pigment epithelium in pigmented small choroidal tumors observed in swept source OCT

Poster Details

First Author: D.Pelayes ARGENTINA

Co Author(s):    A. Folgar   J. Zarate   D. Buonsanti   I. Ibarra                    

Abstract Details


In pigmented small choroidal tumors, complex retinal pigment epithelium - Bruch membrane has been considered a key point in the development and evaluation of these tumors, new technologies such as the SS-OCT allow us to study these areas with high resolution. We report 15 cases of these tumours studying the complex retinal pigment epithelium - Bruch membrane with SS-OCT.


MOS Maimonides Ophthalmology School, Maimonides University, Buenos Aires, Argentina. Ophthalmological centre investigation and development (COID), Maimonides University, Buenos Aires, Argentina.


We included 15 eyes of 15 patients with choroidal tumors small pigmented which we regard as (less than 3 mm in height and less than 10 mm base) to which underwent complete eye examination and imaging With swept-source OCT ( SS-OCT), fluorescein angiography, autofluorescence and ultrasonography. For SS-OCT, to scan acquisition protocol was used Involving 12, 6 and 3 mm horizontally and vertically scans in the posterior fundus. We classify Bruch's membrane as : 1- unchanged , 2- tuned or elongated, 3- microcracks , 4- break. ; and the pigment epithelium predominantly 1- hypotrophic , 2- atrophic , 3- hyperplastic , 4- unchanged. The follow-up was 18 months.


Patients in the study were 9 males and 6 females with an age range (39-72 years). We found in the observation that SS- OCT Bruch's membrane: 1- unchanged 0 patients (0%), 2- tuned or elongated: 9 patients (60%), 3- microcracks: 12 patients (80%), 4- break: 3 patient (20%); and the pigment epithelium as predominantly 1- hypotrophic: 3 patients (20%), 2- atrophic: 0 patients (0%), 3- hyperplastic: 9 patients (60%), 4- unchanged: 0 patients (0%) . In the 4 patients (27%) had growth and characteristics of malignancy of which we saw as elongation findings and / or microcracks of Bruch's membrane 4 patients (100%), combined disorders of the retinal pigment epithelium as predominantly hyperplasia 4 patients (100 %).


We observed in our patient monitoring changes in the retinal pigment epithelium predominantly hyperplastic changes and in Bruch's membrane such as elongation and thinning microcracks had a was associated with growth and / or development of malignant lesions. New technologies such as the SS-OCT could provide data on clinical evaluation in these tumors are difficult to diagnose.

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