First Author: M.Onen TURKEY
Co Author(s): N. Alimova Z. Yazar O. Evren Kemer
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To evaluate the potential association between fundus autofluorescence (FAF), spectral-domain optical coherence tomography, and best corrected visual acuity (BCVA) in patients undergoing 25-gauge vitrectomy because of idiopathic epiretinal membranes.
A retrospective, observational case series, single centre
Retrospective, interventional case series including 23 patients submitted to 25- gauge vitrectomy because of symptomatic idiopathic epiretinal membranes. Studied variables included FAF, photoreceptor inner segment/outer segment (IS/OS) junction line integrity, external limiting membrane (ELM) integrity, central foveal thickness (CFT), and ganglion cell inner plexiform layer (GCIPL) thickness. All examinations were repeated at the first, third, and sixth postoperative months. Foveal AF images were defined as normal AF, hypo-AF and hyper-AF.
BCVA improved significantly (Baseline BCVA: LogMAR 0.73±0.34, 6 month BCVA LogMAR 0.51±0.35 p=0.02) and CFT decreased (Baseline CFT: 432.3±55.1μ, 6 month 404.9±62.9μ, p=0.09) from baseline at 6 months. While hypo-AF was observed preoperatively in 7 eyes (30%) and hyperAF in 2 eyes ( 9%), hypoAF was observed postoperatively in 8 eyes (35%) and hyper-AF in 3 eyes (13%). There was no correlation between postoperative BCVA and preoperative FAF images. There was an association between increased CFT and preoperative hypo-AF (r=0.45, p=0.04). There was no correlation between appearances of FAF and ELM, IS/OS integrity and GCIPL thickness in SD OCT.
The results of this study showed that FAF imaging in patients with idiopathic ERM is not a prognostic factor. Preoperative hypo-AF was associated with increased CFT.