First Author: N.Shahbazova AZERBAIJAN
Co Author(s): M. Karimov U. Ismaylova
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to evaluate the functional state of the retina in patients with diabetic macular edema using modern research methods
multifocal ERG, microperimetry, optical coherence tomography,diabetic maculopathy
we examined 20 patients, 22 eyes. The average age of patients was 57±15 years. All patients were diagnosed with diabetic macular edema. All patients in addition to standard research methods were carried out: multifocal electroretinography (mf-ERG) (Retiscan, Roland Consult, Germany), optical coherence tomography (OCT) (Carl Zeiss Meditec, USA, CA) and microperimetry (microperimeter MAIA, centreVue, Italy). .
in the OCT revealed the deformation of the retinal profile. The average thickness of the retina made up 347µ±106µ. Our study showed that the average density of the bioelectric response of the macular area of the retina in patients with macular edema is sharply reduced and amounts to P1=41,796±24,8 nv/deg., at the rate of P1=66,6-130,87 nv/deg. The average sensitivity (average threshold) according microperimetry made up 17.78±4,2 dB (norm of 23 to 25 dB). These figures show a decline in functional activity and light sensitivity of the retina. The results of correlation analysis (Pearson criterion) found a negative correlation (r=-0,442) between the morphological changes in the central zone of the retina according to the OCT and functional performance according to the mf-ERG. A negative correlation was also identified between indicators of OCT and microperimetry (r=-0,587). Between sensitivity according microperimetry and functional activity of the retina according to the mf-ERG (r=0,356) noted a positive correlation.
based on these data, it is possible to judge that the DMO is an increase in the retinal thickness, which is accompanied by depression of the amplitude of mf-ERG and a decrease in light sensitivity. A pattern is revealed between morphological parameters foveal zone, its bioelectrical activity and light sensitivity.