Posters

Assessment of the functional state of the retina in patients with diabetic macular edema with modern research methods

Poster Details

First Author: N.Shahbazova AZERBAIJAN

Co Author(s):    M. Karimov   U. Ismaylova                          

Abstract Details



Purpose:

to evaluate the functional state of the retina in patients with diabetic macular edema using modern research methods

Setting:

multifocal ERG, microperimetry, optical coherence tomography,diabetic maculopathy

Methods:

we examined 20 patients, 22 eyes. The average age of patients was 57±15 years. All patients were diagnosed with diabetic macular edema. All patients in addition to standard research methods were carried out: multifocal electroretinography (mf-ERG) (Retiscan, Roland Consult, Germany), optical coherence tomography (OCT) (Carl Zeiss Meditec, USA, CA) and microperimetry (microperimeter MAIA, centreVue, Italy). .

Results:

in the OCT revealed the deformation of the retinal profile. The average thickness of the retina made up 347µ±106µ. Our study showed that the average density of the bioelectric response of the macular area of the retina in patients with macular edema is sharply reduced and amounts to P1=41,796±24,8 nv/deg., at the rate of P1=66,6-130,87 nv/deg. The average sensitivity (average threshold) according microperimetry made up 17.78±4,2 dB (norm of 23 to 25 dB). These figures show a decline in functional activity and light sensitivity of the retina. The results of correlation analysis (Pearson criterion) found a negative correlation (r=-0,442) between the morphological changes in the central zone of the retina according to the OCT and functional performance according to the mf-ERG. A negative correlation was also identified between indicators of OCT and microperimetry (r=-0,587). Between sensitivity according microperimetry and functional activity of the retina according to the mf-ERG (r=0,356) noted a positive correlation.

Conclusions:

based on these data, it is possible to judge that the DMO is an increase in the retinal thickness, which is accompanied by depression of the amplitude of mf-ERG and a decrease in light sensitivity. A pattern is revealed between morphological parameters foveal zone, its bioelectrical activity and light sensitivity.

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