Posters

Evaluation of optic disc, retinal nerve fibre and macular ganglion cell layers in paediatric diabetes

Poster Details

First Author: G.Pekel TURKEY

Co Author(s):    S. Altincik   G. Pekel                          

Abstract Details



Purpose:

Our aim was to compare optic disc parameters, retinal nerve fibre (RNFL) and macular ganglion cell layers between children and adolescents with diabetes mellitus (type 1) and healthy controls.

Setting:

Denizli State Hospital, Eye Clinic, Denizli, Turkey

Methods:

Sixty-three eyes of 63 paediatric diabetic patients without diabetic retinopathy and 44 eyes of 44 healthy controls were included in this cross-sectional and comparative study. Diabetic and control groups were similar in the aspect of age, gender and refractive error. Measurements of optic disc parameters (i.e., rim area, disc area, cup to disc ratio, cup volume), thickness of RNFL and macular ganglion cell-inner plexiform layers (GCL+IPL) were taken with the spectral domain optical coherence tomography.

Results:

There were not statistically significant differences between the diabetic patients and healthy controls in terms of intra-ocular pressure (p=0.14), retinal nerve fibre layer thickness (p=0.61), rim area (p=0.92), disc area (p=0.10), vertical cup to disc ratio (p=0.16), cup volume (p=0.13), and average macular GCL+IPL thickness (p=0.43). On the other hand, binocular RNFL thickness symmetry percentage was statistically significantly different in the diabetic and control groups (p=0.01) and it was negatively correlated with the blood HbA1c level (r=-0.28, p=0.026).

Conclusions:

Diabetic children and adolescents without retinopathy have more binocular RNFL thickness asymmetry compared to healthy controls. Binocular RNFL thickness symmetry is adversely affected by the poor glycemic control in DM (type 1).

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