Posters

Subthreshold yellow micropulse laser 577nm therapy- A new therapeutic approach in the treatment of diabetic macular edema

Poster Details

First Author: M.Latalska POLAND

Co Author(s):    A. Prokopiuk                             

Abstract Details



Purpose:

To evaluate the efficacy of subthreshold micropulse yellow (577 nm) laser photocoagulation in diffuse macular edema (DME) for diabetic macular edema.

Setting:

Laser therapy has been replaced by anti-VEGF therapy in the treatment of diabetic macular edema. Is micropulse laser therapy can make a difference?

Methods:

The examined group consisted of 46 females and 29 males, aged 26-83 years (mean age 67±8.0) with diffuse diabetic macular edema treated in Department of Vitreoretinal Surgery of Medical University of Lublin received 1 to 4 sessions of laser photocoagulation (IRIDEX OcuLight IQ 577nm) in two-months intervals, with a 5% duty cycle at an energy level. The laser exposure time was 20 ms and the spot diameter was 200 µm. Median duration of DM in treated group was 15±10 years (ranged 1-39), median glycated haemoglobin- HbA1c level was 7.3±0.96 (ranged 6.1-9.78%). The SD-OCT was performed to evaluate the central retinal thickness before treatment and in two month intervals. Further, we measured visual acuity for distance and reading vision.

Results:

The follow-up was 6 months. The baseline median BCVA was 0.20±0.27 and remained stable: 0.30±0.37 after 6 months (p=0.0019*). The median reading vision improved from 1.0±1.0 at baseline to 0.5±1.2 at final follow-up ( p=0.00042*). The median CRT at baseline was 500±205 µm and decreased significantly to 346±153 µm (p=0.00000*) at the final follow-up. Finally, no retinal damage was observed. We obtained statistically significant reduction in central retinal thickness, stabilization of visual acuity for distance and improving in reading visual acuity.

Conclusions:

Subthreshold yellow micropulse laser showed short-term efficacy in the treatment of DME. It allows to obtain a therapeutic effect at lower level of energy, which limits the laser-induced heat to spread to adjacent tissues and avoids to demage the retinal layers.

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