Posters

Intravitreal ranibizumab therapy for symptomatic retinal arterial macroaneurysm

Poster Details

First Author: M.Kaya TURKEY

Co Author(s):    N. Kocak   T. Ozturk   Z. Ayhan   S. Kaynak                    

Abstract Details



Purpose:

To evaluate the anatomic and functional results of intravitreal ranibizumab injection for treatment of symptomatic retinal arterial macroaneurysm (RAM).

Setting:

Dokuz Eylul University School of Medicine, Izmir, Turkey.

Methods:

Retrospective interventional case series. A series of seven patients (seven eyes) who had been diagnosed with symptomatic RAM were assessed by comprehensive ophthalmologic examination, fluorescein angiography (FA), and spectral domain optical coherence tomography (SD-OCT). All patients were treated by intravitreal ranibizumab injection within two week of diagnosis and retreated upon evidence of persistent serous detachment or haemorrhage involving the macula on SD-OCT. Anatomical recovery was examined by FA, and OCT. Best-corrected visual acuity (BCVA) and central macular thickness (CMT) were evaluated using the Snellen chart and optical coherence tomography, respectively, at baseline; at 1, 2, 3, and 6 months; and at the final visit.

Results:

The mean follow-up period for all subjects was 14.64 ± 5.2 months. The mean number of injections for the RAM was 1.57 ± 0.64. The mean logarithm of the minimal angle of resolution (LogMAR) of BCVA improved from 0. 96 ± 0.56 to 0.14± 0.12 (p = 0.012) and mean CMT decreased from 456.4 ± 145.6 μm to 216.8 ± 32.4 μm (P = 0.024). No complications were observed with intravitreal ranibizumab injection.

Conclusions:

Intravitreal ranibizumab is an effective therapy for symptomatic RAM, quickly improving BCVA and CMT. Intravitreal ranibizumab injection likely hastens resolution of macular edema and haemorrhage secondary to RAM.

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