Posters

Bevacizumab in proliferative diabetic retinopathy; Pilot study comparing retinal photocoagulation versus intravitreal bevacizumab

Poster Details

First Author: M.Iqbal PAKISTAN

Co Author(s):    A. Aftab                             

Abstract Details

Purpose:

We compared the beneficial effects of intravitreal bevacizumab (IVB) versus PRP in regression of new vessels in treatment naïve eyes with PDR.

Setting:

Khyber Teaching Hospital, Peshawar, Pakistan

Methods:

This randomized control trial pilot study was conducted to evaluate the feasibility of the multicentre trial. Patients with treatment naïve PDR were recruited. Randomization was carried out using a custom made software. Pre-treatment examination was carried out including fluorescein angiography and optical coherence tomography. Area of leakage on FFA was measured in mm2 using the custom made software. In IVB group 4 weekly injections were administered for 3 months. In PRP group, PASCAL laser was used to carry out macular grid and PRP in two sessions at least 4 weeks apart. After 3 months of treatment repeat FFA and OCT ware performed

Results:

Eyes included in this trial were 9 eyes from 5 patients. 5 patients were randomized into IVB group while 4 patients were in PRP group. IVB group had complete regression of leakage (92.42 ± 159.48 mm2 vs zero mm2), while PRP group demonstrated partial regression (499.22 ± 465.19 mm2 vs 74.00 ± 86.31 mm2) at 12 weeks.

Conclusions:

IVB seems superior to PRP in regression of new vessels in treatment naïve eyes with PDR at least in the short term