First Author: A.Garrido Hermosilla SPAIN
Co Author(s): M. Mendez Muros E. Gutierrez Sanchez C. Morales Portillo M. Diaz Granda E. Esteban Gonzalez E. Rodriguez de la Rua Franch
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To examine the relationship between foveal avascular zone (FAZ) and renal function tests.
Retina Unit, Ophthalmology Department, Virgin Macarena University Hospital (Seville, Spain). RETICS OftaRed, Institute of Health Carlos III (Madrid, Spain). Diabetes Unit, Endocrinology and Nutrition Department, Virgin Macarena University Hospital (Seville, Spain).
Cross-sectional study with 42 eyes of 21 ocular treatment-naïve diabetic patients. Demographic and ocular data were analyzed as well as the following renal function tests: microalbuminuria, microalbumin/creatinine ratio and glomerular filtration rate (CKD-EPI and MDRD-4). Superficial (sFAZ) and deep (dFAZ) foveal avascular zones were measured using swept-source ocular coherence tomography angiography (SS OCT-A).
The mean age was 49,76 ± 17,61 years old (18-74), with a sex ratio of approximately 1:1. 66.7% suffered from type 2 diabetes mellitus, with a mean time of evolution of 12,14 ± 10,08 years. 51.2% of patients didn’t present diabetic retinopathy. Among renal function tests, only microalbuminuria negatively correlated with both sFAZ and dFAZ (p<0,05).
The analysis of FAZ with SS OCT-A could be a prediction tool of renal function in diabetic patients.