First Author: C.Tsen TAIWAN
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To describe the clinical manifestations in patients with acquired immunodeficiency syndrome (AIDS) who had uveitis as an initial features
Retrospective chart review of all the patients diagnosed as AIDS with ophthalmic examination records from January 2006 to November 2015 was performed in a tertiary referral centre in Southern Taiwan
Retrospective chart review of all the patients diagnosed as AIDS with ophthalmic examination records from January 2006 to November 2015 was performed in a tertiary referral centre in southern Taiwan. Data variables included age, sex, ophthalmic examinations, systemic conditions, CD4 counts, course and treatment.
Eleven patients were identified as AIDS with uveitis as presenting manifestation. All were males, with mean age of 39.5 ± 11.4 years (range 24-56). The mean of CD4+T cell counts was 91.7 ± 50.3 cells/μL (range: 27-169). Ocular diagnosis included cytomegalovirus (CMV) retinitis in 5 patients, ocular syphilis in 4 patients and ocular toxoplasmosis in 2 patients. Seven patients had bilateral involvement, and four patients had unilateral involvement. Uveitis resolved in all patients after medical treatment. However, retinal detachment developed in 2 eyes with CMV retinitis and one eye with ocular syphilis.
Ocular manifestations are among the most common clinical features in HIV/AIDS patients having various clinical presentations affecting almost all the structures of the eye. Moreover, the ocular findings can be the initial manifestation of the underlying disease. Awareness on ocular lesions in AIDS is important for their early recognition and management.