Posters

Increased photoreceptor outer segment volume following systemic treatment of birdshot chorioretinopathy

Poster Details

First Author: R.Martens CANADA

Co Author(s):    G. Docherty   F. Forooghian                          

Abstract Details



Purpose:

Retinal degeneration in birdshot chorioretinopathy (BSCR) can be quantified using spectral-domain optical coherence tomography (SD-OCT) by measuring the photoreceptor outer segment (PROS) volume. The purpose of this study was to determine if PROS volume in BSCR responds to systemic immunomodulatory therapy (IMT).

Setting:

University of British Columbia

Methods:

Retrospective chart review with analysis of PROS volume derived from standard domain OCT (SD-OCT).

Results:

We identified a total of three patients who met our inclusion criteria. At baseline, all patients had abnormal PROS and/or ellipsoid layer findings on SD-OCT. Following systemic IMT, these abnormalities resolved, and PROS volume increased in all patients (p < 0.05).

Conclusions:

PROS volume can increase following systemic treatment of BSCR. This SD-OCT parameter may serve as a useful marker of retinal degeneration in BSCR, and may be a useful outcome measure in monitoring treatment response in BSCR.

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