Increased photoreceptor outer segment volume following systemic treatment of birdshot chorioretinopathy

Poster Details

First Author: R.Martens CANADA

Co Author(s):    G. Docherty   F. Forooghian                          

Abstract Details


Retinal degeneration in birdshot chorioretinopathy (BSCR) can be quantified using spectral-domain optical coherence tomography (SD-OCT) by measuring the photoreceptor outer segment (PROS) volume. The purpose of this study was to determine if PROS volume in BSCR responds to systemic immunomodulatory therapy (IMT).


University of British Columbia


Retrospective chart review with analysis of PROS volume derived from standard domain OCT (SD-OCT).


We identified a total of three patients who met our inclusion criteria. At baseline, all patients had abnormal PROS and/or ellipsoid layer findings on SD-OCT. Following systemic IMT, these abnormalities resolved, and PROS volume increased in all patients (p < 0.05).


PROS volume can increase following systemic treatment of BSCR. This SD-OCT parameter may serve as a useful marker of retinal degeneration in BSCR, and may be a useful outcome measure in monitoring treatment response in BSCR.

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