First Author: S.Kaynak TURKEY
Co Author(s): M. Kaya T. Ozturk N. Kocak
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To study the efficacy of a single 0.7 mg dexamethasone intravitreal implant in vitrectomized eyes with refractory macular edema secondary to silicone oil tamponade.
Dokuz Eylul University, Department of Ophthalmology
Four eyes of 4 consecutive patients with refractory macular edema secondary to 23-gauge pars plana vitrectomy and silicone oil tamponade for rhegmatogenous retinal detachment were included. Injection of the 0.7 mg dexamethasone implant was performed following the surgery for silicone oil removal. Best-corrected visual acuity (Snellen) and central retinal thickness were measured by spectral domain optical coherence tomography, and intraocular pressure was evaluated at baseline, 1 month, 3 months and 6 months.
After a mean follow-up of 5.35 ± 0.62 months, best-corrected visual acuity was significantly increased from 0.35±0.2 to 0.76±0.6 (P < 0.0001), mean central retinal thickness decreased significantly from 452 ± 36 μm to 285 ± 38 μm (P < 0.0001), and intraocular pressure changed significantly (P = 0.02) from 14.24 ± 1.08 to 16.2 ± 0.85. Macular edema was observed in one case with partial resolution. Postoperative hypotony or other complication was not observed in any cases.
A single injection of the 0.7 mg dexamethasone intravitreal implant resulted effective in the treatment of refractory macular edema secondary to silicone oil tamponade for rhegmatogenous retinal detachment allowing recovery in visual acuity.