Central serous chorioretinopathy treatment with eplerenone and spironolactone: A challenging case

Poster Details

First Author: S.Engur Goktas TURKEY

Co Author(s):    T. Celik                             

Abstract Details


To present a case of central serous chorioretinopathy (CSC) treatment with eplerenone and spironolactone in a challenge pattern.


A 33-year-old male accountant presenting with CSC. The patient had been treated by initial medical therapy (oral carbonic anhydrase inhibitor, oral antihistamines, systemic/topical non-steroidal anti-inflammatory drugs and selective serotonin re-uptake inhibitor) and micropulse laser treatment.


At presentation the best corrected visual acuities (BCVA) of the right and left eyes were 1.0/0.1, respectively. Optical coherence tomography (OCT) was performed on both eyes. The patient was prescribed 25 mg eplerenone daily for 8 weeks and subsequently spirinolactone 50mg for 4 weeks along with serum potassium monitoring. At follow-ups, OCT was performed.


Eplerenone and spironolactone treatment resolved the CSC. The final BCVA of the right and left eyes were 1.0/1.0, respectively. The CSC did not repeat after discontinuation the treatment. CSC totally resolved.


Eplerenone and spironolactone therapy was an effective treatment of CSC in this case.

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