Posters

Swept source optical coherence tomography angiography in choroidal melanoma

Poster Details

First Author: M.Pellegrini ITALY

Co Author(s):    F. Corvi   G. Staurenghi                          

Abstract Details



Purpose:

To describe the imaging features of choroidal melanoma using swept source optical coherence tomography angiography (OCT-A) and evaluate its ability to display tumour intrinsic vasculature.

Setting:

Retrospective observational case series conducted at the Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan.

Methods:

Patients with choroidal melanoma underwent a complete ophthalmic evaluation, including best corrected visual acuity, colour fundus photography, B-scan ultrasound, fluorescein angiography (FA), indocyanine green angiography (ICGA) and swept source OCT-A with Zeiss prototype (PLEX Elite, Swept-Source OCT model 9000, Carl Zeiss Meditec, Inc, Dublin, CA).

Results:

Twenty-two eyes of 22 consecutive patients with choroidal melanoma were included in the study; 11 cases (50%) were treatment naïve. Three lesions (14%) were located at the macula, 14 (63%) between the macula and equator and 5 (23%) between the equator and the ora serrata. The mean tumour base and thickness were respectively 10.3 mm (range 5-15 mm) and 4.5 mm (range 1.5-8.9 mm). Seventeen lesions (77%) were dome shaped whereas 5 (23%) showed a mushroom configuration. Thirteen lesions (59%) were pigmented, 5 (23%) partially pigmented and 4 (18%) amelanotic. An exudative retinal detachment was detected in 13 eyes (59%). FA and ICGA disclosed intrinsic microvasculature of the tumour respectively in 4 (20%) and 22 (100%) cases whereas OCT-A detected microvasculature of choroidal melanoma in all cases. Specifically, intrinsic vasculature could be recognized in 14 eyes (64%) using the automated choroid segmentation, 16 eyes (73%) using the automated whole eye segmentation and in 22 eyes (100%) with fine manual adjustments of segmentation lines.

Conclusions:

Swept source OCT-A represents a valid imaging technique in evaluating patients affected by choroidal melanomas. In our series OCT-A disclosed the intrinsic microvasculature of the tumour in all cases despite their size and position.

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