Serous retinal detachments and optic disc swelling in a patient with acute lymphoblastic leukemia during remission

Poster Details

First Author: M.Mestanoglu TURKEY

Co Author(s):    O. Yabas Kiziloglu   O. Gedar   C. Adiguzel   O. Toygar                    

Abstract Details


To describe a patient with acute lymphoblastic leukemia who presented with bilateral serous retinal detachments and right optic disc swelling during hematological remission.


Goztepe Medical Park Hospital, a hospital affiliated with Bahcesehir University School of Medicine


Case report


A 23-year-old woman with acute lymphoblastic leukemia developed bilateral subacute visual loss during hematological remission. Ophthalmologic examination revealed bilateral serous retinal detachments and right optic disc swelling. Magnetic resonance imaging for differential diagnosis was inconclusive; however cerebrospinal fluid sampling demonstrated central nervous system involvement. Second cycle of chemotherapy including intrathecal treatment was instituted and patient’s vision and fundus findings improved in three weeks.


Serous retinal detachment and optic disc swelling are unusual ocular manifestations of acute lymphoblastic leukemia, rarely seen during haematological remission. They may occur due to leukemic infiltration of ocular structures and may indicate extramedullary recurrence of the disease. Early recognition and treatment is crucial to improve prognosis. 

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