First Author: M.Mestanoglu TURKEY
Co Author(s): O. Yabas Kiziloglu O. Gedar C. Adiguzel O. Toygar
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To describe a patient with acute lymphoblastic leukemia who presented with bilateral serous retinal detachments and right optic disc swelling during hematological remission.
Goztepe Medical Park Hospital, a hospital affiliated with Bahcesehir University School of Medicine
A 23-year-old woman with acute lymphoblastic leukemia developed bilateral subacute visual loss during hematological remission. Ophthalmologic examination revealed bilateral serous retinal detachments and right optic disc swelling. Magnetic resonance imaging for differential diagnosis was inconclusive; however cerebrospinal fluid sampling demonstrated central nervous system involvement. Second cycle of chemotherapy including intrathecal treatment was instituted and patient’s vision and fundus findings improved in three weeks.
Serous retinal detachment and optic disc swelling are unusual ocular manifestations of acute lymphoblastic leukemia, rarely seen during haematological remission. They may occur due to leukemic infiltration of ocular structures and may indicate extramedullary recurrence of the disease. Early recognition and treatment is crucial to improve prognosis.