Posters

Correlation between optical coherence tomography angiography and fluorescein/indocyanin green angiography in choroidal neovascularization in wet age-related macular degeneration

Poster Details

First Author: P.Santos Ramos SPAIN

Co Author(s):    M. Fernandez   M. Gil Martinez   M. Rodriguez Cid   M. Abraldes Lopez-Veiga   F. Gonzalez   F. Gomez-Ulla de Irazazabal              

Abstract Details



Purpose:

To analyze choroidal neovascularization (CNV) in wet age-related macular degeneration (AMD) using multi-imaging. To correlate morphologic characteristics as well as CNV types

Setting:

Department of Ophthalmology, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain. Instituto Oftalmológico Gómez-Ulla. Santiago de Compostela. Spain

Methods:

All patients were evaluated with fluorescein angiography (Spectralis HRA; Heidelberg Engineering, Heidelberg, Germany) and optical coherence tomography angiography (OCT-A) (Angioplex, Cirrus HD-OCT models 5000; Carl Zeiss Meditec, Inc, Dublin, OH , DR1 Triton, Topcom corp., Japan). Indocyanine green angiography (ICGA)(Spectralis HRA; Heidelberg Engineering, Heidelberg, Germany) images were acquired in patients with suspected polipoidal choroidal vasculopathy or type III CNV

Results:

We have analyzed 63 eyes of 59 patients diagnosed with wet AMD. Standard CNV classification was followed in this study: type I, II, III and PCV. Correlation between both techniques was obtained in 97.61% in patients with type I CNV, 91.66% of type II, 100% of type III and 100% of mixed (type I + type II). Polipoidal lesions were not identified in any of the patients with PCV using OCT-A.

Conclusions:

OCT-A is a fast, non-invasive technique useful in CNV. It allows to visualize Type I CNV and the hidden component of mixed CNV better than FA due to its location under the RPE, except when a high RPE detachment exists. In this cases it has been helpfull making a manual layer segmentation looking carefully for CNV. OCT-A has been specially useful to detect type I CNV without intraor subretinal fluid on OCT and to display the feeder vessel. ICGA has proven to be more useful in identifying polipoidal lesions in PCV whereas OCT-A allows to see the branching vascular networks in this condition.

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