First Author: E.Peiretti ITALY
Co Author(s): E. Peiretti G. Caminiti C. Iovino R. Serra
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To evaluate the OCT-Angiography (OCT-A) characteristics in patients with chronic central serous chorioretinopathy (CSCR) complicated with polypoidal vasculopathy (PCV).
Retrospective study of patients affected by chronic CSCR complicated by PCV
12 eyes of 10 consecutive patients with an history of chronic CSCR have been evaluated with complete ophthalmological examination including fluorescein angiography (FA) and indocyanine green angiography (ICGA) and SD-OCT (HRA+OCT Spectralis Heidelberg), that revealed the presence of polypoidal lesions with their neovascular network. The patients were then scanned with OCT-A, using AngioVue technologies (Optovue Inc), in order to define the characteristics of those lesions previously observed on multimodal imaging. Three independent physicians analyzed the OCT-A images.
OCT-A segmentation analysis of different layers confirmed the presence of the neovascular network in 100% of the eyes, while the polyps were seen in 8 eyes (66.6%) and not detectable in 4 eyes (33.3%), on the basis of the ICGA matching images. The polyp lesions appeared either as an hyperreflective aneurysmatic dilatation surrounded by a dark halo or as an hyporeflective round area was seen in the polyp location. The observers were in agreement in most of cases.
OCT-A appears to be less precise compared to ICGA in order to detect the presence of the polyps, although the neovascular network was always detectable with both machines in patients with PCV complicating chronic CSCR.