Evaluation of central macular thickness and retinal nerve fibre layer thickness in patients with Wilson's disease: A pilot study

Poster Details

First Author: N.Kara TURKEY

Co Author(s):    S. Seyyar   O. Saygili   M. Seyyar   M. Gulsen                    

Abstract Details


The aim of the study was to evaluate central macular thickness (CMT) and retinal nerve fibre layer (RNFL) thickness using spectral-domain optical coherence tomography (SD-OCT) in patients with Wilson's Disease (WD).


This study was performed in the Department of Ophthalmology, Gaziantep University School of Medicine, Gaziantep, Turkey.


Twenty-six subjects, 13 with Wilson's disease (study group) and 13 with healthy controls (control group), were enrolled in this prospective and comparative study. All patient underwent clinical examination followed by measurements of central macular thickness and RNFL thickness by SD-OCT. One eye of each patient was analyzed using 1-way Anova test.


The average age of subjects was 31±11 D in the study group and 30±10 D in the control group. Mean CMT was 272±15 µm in the study group and 263±19 µm in the control group (p>0.05). There was no statistically significant differences in peripapillary RNFL thickness in patients with WD and healthy controls (p>0.05).


This study showed that CMT and RNFL thicknesses in all quadrants did not differ significantly between the groups.

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