First Author: S.Kadayifcilar TURKEY
Co Author(s): O. Inam B. Eldem
Back to previous
To assess choroidal paremeters in patients with central serous chorioretinopathy (CSC) employing an image binarization tool on enhanced depth imaging (EDI) scans obtained with spectral domain optical coherence tomography (OCT).
University Hospital Ophthalmology Department
64 eyes of 32 active CSC patients, 62 eyes of 31 chronic CSC patients and 33 eyes of 33 healthy subjects were included in this retrospective study. Acute CSC eyes were gathered in group-1, chronic CSC eyes in group-2, control eyes in group-3, fellow eyes of active CSC in group 4 and fellow eyes of chronic CSC in Group 5 . Demographic factors were obtained from hospital records. With EDI mode of Heidelberg Spectralis OCT, choroidal images were obtained with a radius of 1500µm subfoveally and binarized to luminal and stromal areas. Choroidal vascularity index (CVI) was calculated by dividing luminal area (LA) to total choroidal area (TCA) which is LA + stromal area (SA). Stromal area percent (SAP) was calculated as stromal choroidal area (SA) divided by TCA. Luminal to stromal ratio (LSR) was calculated as LA divided by SA. Means of macular thickness (MMT), subfoveal choroidal thickness (SCT), TCA, LA, SA, CVI, SAP and LSR values were compared between the groups employing Student’s t test.
Groups had similar female to male ratios. Mean age was 44.91±7.67 for active CSC, 49.03±11.79 for chronic CSC, and 47.09±11.62 for controls (p=0.512). Subfoveal choroid was significantly thicker in all groups when compared to controls. Macular thickness was most prominent in the active CSC group. TCA, LA and SA values were significantly higher in both CSC groups whan compared to controls, however fellow eyes did not show significant difference. CVI, SAP or LSR did not differ significantly among the groups.
In this study, SCT, TCA, LA and SA were significantly higher in active and chronic CSC. CVI, which was proposed as an index for early diagnosis of CSC in other studies, was not found to be significantly different when compared to either fellow eyes or healthy control eyes.