Posters

OCT-Angiography in the study of haemodynamic abnormalities in central serous chorioretinopathy

Poster Details

First Author: T.Iureva RUSSIA

Co Author(s):    A. Shchuko   A. Zlobina   S. Zhukova   V. Bukina                    

Abstract Details



Purpose:

Retinal pigment epithelium (RPE) alteration in patients with central serous chorioretinopathy (CSCR) is generally explained by the disturbance of choroidal circulation that makes haemodynamics changes in different forms of CSCR an interesting topic for the study. Purpose: To study diagnostic value of OCT-Angiography in choroidal circulation examination in CSCR and to find correlations between haemodynamics changes and RPE alteration in different CSCR forms.

Setting:

Irkutsk Branch of S. Fyodorov Eye Microsurgery Federal State Institution, Irkutsk, Russia

Methods:

26 patients with CSCR were divided into two groups: 1) 9 patients with acute CSCR, 2) 17 patients with chronic CSCR. Control group included 20 patients without any ocular pathology. To study chorioretinal circulation OCT-Angiography (“Optovue XR Avanti”, USA) was applied.

Results:

Acute form of CSCR characterized by the significant increase of choroidal vessels diameter and choroidal thickness both in eyes with CSCR (487.5±120.3 μm compared to 246.8±48.5, p<0.01 in the controls) and in fellow eyes (372.2±87.6 μm). There was an increase of choroidal reflectivity and decrease of choroidal thickness by 25.6% in chronic CSCR compared to the acute form. Nevertheless, choroidal thickness in chronic CSCR (362.5±27.1 μm) was higher (by 46.9%) than in the control group. Layerwise OCT-Angiography of choroid in acute CSCR revealed the decrease of choriocapillaries reflectivity that indicates slowing-down of blood flow. The diameter of medium- and large-caliber vessels was increased. Chronic CSCR characterized by the increase of vessel wall reflectivity and blood flow slowing-down in choriocapillaries layer. Long-persistent choroidal dysfunction was accompanied by retina dystrophic changes and complicated by CNV in 23.5% cases. In patients with combination of neuroepithelium and RPE detachment the changes in choroid were even more pronounced. In the projection of RPE detachment foci of altered chorocapillaries were visualized.

Conclusions:

OCT-Angiography is a valuable tool for choroidal circulation visualization, the study of type and extent of structural changes of the choroid and haemodynamic abnormalities in different forms of CSCR.

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