First Author: F.Hamzah INDONESIA
Co Author(s): A. Shinojima H. Nakashizuka H. Shimada
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To analyze the foveal avascular zone area (FAZ) in macular hole (MH) patients preoperatively and 6-month postoperatively at the superficial vascular and deep vascular layer levels, for comparison with a control group.
Nihon University Hospital, Tokyo, Japan.
Descriptive study, retrospective case series. We studied 14 eyes of 14 consecutive patients (4 men, 10 women) with unilateral MH. We examined all cases before and 6 months after surgery using Spectral domain-OCT and OCT-Angiography (OCT-A). OCT-A images were acquired within a 3 x 3 mm area at the foveal centre.
Mean age was 65.6 ± 6.6 years. The mean superficial layer preoperative FAZ (0.45 ± 0.09 mm2) was larger than the postoperative FAZ (0.25 ± 0.09 mm2) (P < 0.001). The mean deep-layer preoperative FAZ (0.79 ± 0.39 mm2) was larger than the postoperative FAZ (0.31 ± 0.12 mm2) (P < 0.001). The mean superficial layer preoperative FAZ was the same as that of the fellow eye (control group: 0.41 ± 0.10 mm2) (P=0.23). The mean superficial postoperative FAZ was smaller than that of the fellow eye (P <0.001). The mean deep layer preoperative FAZ was larger than that of fellow eye (0.48 ± 0.11 mm2) (P = 0.019). The mean deep layer postoperative FAZ was smaller than that of fellow eye (P < 0.001).
The FAZ was larger preoperatively than postoperatively in both the superficial and deep layer. The mean superficial layer preoperative FAZ was the same as that of the control group. The deep plexus layer might affect MH formation.