Unique feature of best vitelliform macular dystrophy on optical coherence tomography angiography

Poster Details

First Author: M.Abrishami IRAN

Co Author(s):    A. Mirshahi   A. Masoumi                          

Abstract Details


To report three cases of best vitelliform macular dystrophy (BVMD) with an intriguing pattern of vascular flow on optical coherence tomography angiography (OCT-A).


Eye Research centre, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran


Adult human subjects who were diagnosed with BVMD were evaluated by OCT-A. All participants underwent complete ophthalmic examination, including best corrected visual acuity (BCVA), fluorescein angiography, spectral domain optical coherence tomography, electroretinography, and electrooculography testing. OCT-A was performed with a scanning area of 3×3 mm centreed on the fovea. Images were manually segmented to verify the accuracy of the automated segmentation algorithms.


Three patients with BVMD were evaluated. The first patient had macular lesions at the pseudohypopyon and vitelliruptive stages with BCVA values of 10/10 and 20/32, respectively. The second patient had a BCVA of 20/60 in the left eye and 20/25 in the right eye. Dilated fundoscopy revealed that the left eye had developed choroidal neovascularization. A macular lesion at the vitelliform stage was observed in the right eye. The last patient had pigmentary macular changes consistent with a diagnosis of BVMD. In both eyes, BCVA was 10/10. OCT-A revealed a bridging vessel in the foveal avascular zone in five eyes and a dense subretinal capillary network in one eye with choroidal neovascularization.


The presence of a bridging vessel in the foveal avascular zone of patients with BVMD might have important clinical implications. Further studies are needed to evaluate the clinical utility of this finding.

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