Posters

Foveal avascular zone area analysis of epiretinal membrane before and after surgery optical coherence tomography (OCT) angiography

Poster Details

First Author: Y.Kitagawa JAPAN

Co Author(s):    A. Shinojima   H. Nakashizuka   H. Shimada                       

Abstract Details



Purpose:

To analyze the foveal avascular zone area (FAZ) in epiretinal membrane (ERM) patients preoperatively and 6 months postoperatively at the superficial vascular and deep vascular layer levels, for comparison with a fellow-eye control group.

Setting:

OCT-A findings have been reported in a variety of fundus abnormalities. However, the effects of ERM formation and its remomval on the FAZ have not been examined by OCT-A.

Methods:

Descriptive study, retrospective case series. We studied 13 eyes of 13 consecutive patients (5 men, 8 women) with unilateral ERM. We examined all cases before and 6 months after surgery using Spectral domain-OCT and OCT-Angiography (OCT-A). OCT-A images were acquired within a 3 x 3 mm area at the foveal centre.

Results:

Mean age was 64.4 ± 8.8 years. The mean preoperative FAZ in the superficial layer (0.056 ± 0.029 mm2) was smaller than the postoperative FAZ (0.080 ± 0.038 mm2) (P < 0.0001). The mean preoperative FAZ in the deep layer (0.082 ± 0.035 mm2) was smaller than the postoperative FAZ (0.113 ± 0.045 mm2) (P < 0.0035). The mean preoperative FAZ in the superficial and deep layers were the same as those of the fellow eye (control group: 0.295 ± 0.108 mm2, 0.410 ± 0.142 mm2). The mean superficial postoperative FAZ was smaller than that of the fellow eye (P < 0.0001). The mean postoperative FAZ in the deep layer was smaller than that of fellow eye (P < 0.0001). The factors affecting the mean postoperative FAZ in the superficial and deep layers were the mean preoperative FAZ in these layers (P < 0.0001, P = 0.0045). There was no correlation of postoperative FAZ with visual acuity, metamorphopsia score using M-CHARTS, or aniseikonia score using the New Aniseikonia test.

Conclusions:

OCT-Angiography revealed that ERM reduces FAZ size. Removing the ERM clearly improved the FAZ at 6 months postoperatively, though not as extensively as in the fellow eyes.

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