First Author: H.Wong SINGAPORE
Co Author(s): C. Tan
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To describe the demographics of patients with Polypoidal Choroidal Vasculopathy in an Asian tertiary eye centre.
The study was carried out in a tertiary eye centre at Tan Tock Seng Hospital, National Healthgroup Eye Institute, Singapore.
Retrospective review of case notes were performed from January 2015 to December 2016. Data collected included demographics, gender, laterality, presenting eye signs and treatment modalities.
A total of 45 eyes of 40 patients were reviewed of which 91.1% (41/45) were Chinese, 4.4% (2/45) were Indian and 4.4% (2/45) were Malay. There were 62.2% (28/45) males and 37.8% (17/45) females. The right eye was affected in 48.9% (22/45) of patients while the left eye was affected in 51.1% (23/45). At initial presentation, 31.1% (14/45) eyes had best corrected visual acuity (BCVA) better than 6/12 while 68.9% (31/45) eyes had BCVA worse than 6/12. Improvement in BCVA was seen in 26.7% (12/45) of patient after treatment. Fourty-four percent (20/45) of the presenting eye signs consisted of submacula haemorrhage, 24.4% (11/45) were haemorrhagic pigment epithelial detachment (PED) and 13.3% (6/45) were macula oedema. Treatment modalities included 55.5% (25/45) of focal laser, 28.8% (13/45) of photodynamic therapy (PDT) and 17.7% (8/45) of intravitreal therapy. For patients who underwent PDT, the mean Greatest Linear Dimension was 3118µm. The mean number of intravitreal injections is 9.
Majority of patients (68.9%) had poor visual acuity at presentation and a significant proportion of them (44.4%) presented with submacula haemorrhage. There were more male than female patients (62.2% vs 37.8%).