First Author: M.Sekeroglu TURKEY
Co Author(s): S. Doguizi P. Yilmazbas
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To present the clinical follow-up of a case of peripheral haemorrhagic chorioretinopathy (PEHC) treated with intravitreal aflibercept injections and to discuss treatment alternatives.
Ulucanlar Eye Training and Research Hospital, Ankara, Turkey
We present a 76-year-old woman with subfoveal exudation secondary to PEHC at the temporal periphery of the left eye. The diagnosis of intraocular malignancy was excluded by using magnetic resonance imaging of the orbita. Her past systemic and ophthalmic history was unremarkable besides hypertension. The visual acuity was 20/25 in the right and 20/200 in the left eye. Anterior segment examination revealed no abnormality, and the intraocular pressure was normal in both eyes. Fundus examination of the right eye was normal; but fundus examination revealed exudation and haemorrhages on the temporal periphery with a secondary subfoveal fluid accumulation on the left eye. Optical coherence tomography of the left eye revealed subfoveal fluid accumulation and retina pigment epithelial detachment with exudation and haemorrhages on temporal quadrant. Decision was taken to treat the patient with intravitreal aflibercept injection.
Subfoveal fluid accumulation was decreased after first dose and subsided after second dose of 2 mg/0.05 ml intravitreal aflibercept injection. The final visual acuity was 20/30 after 2 years without any recurrence with two monthly aflibercept injections.
PEHC is a disease of the peripheral retina that emerges with advancing age. It can spontaneously regress, but the lesions that progress from the periphery to fovea may result in decreased visual acuity and necessitates treatment. Intravitreal aflibercept injection seems to be a new and promising alternative for central involving PEHC.