First Author: Z.Oztas TURKEY
Co Author(s): J. Mentes
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To present the multimodal imaging characteristics of the precursor retinal angiomatous proliferation (RAP) lesions and follow-up results with “Eye-Tracked” spectral-domain optical coherence tomography (SD-OCT).
Ege University Faculty of Medicine, Department of Ophthalmology, Retina Unit, Izmir, Turkey.
Prospective, observational, case series. Six eyes of 6 patients diagnosed as precursor RAP lesion with the mean of 77.5 ± 5.9 years was included in the study. Besides the best-corrected visual acuity (BCVA) and full ocular examination diagnostic features of these precursor lesions and long-term, follow-up results are presented by using fundus photography (FP), fundus autofluorescence (FAF) imaging, SD-OCT, fluorescein angiography (FA), indocyanine green angiography (IGA), and optical coherence tomography angiography (OCT-A).
The mean decimal BCVA was 0.8 ± 0.16 level and the mean follow-up was 26.3 ± 14.8 months. Images of the precursor RAP lesions were demonstrated no specific findings on FP and FAF, focal hypofluorescent foci with no leakage on FA and IGA, and extrafoveal, small, round, well-defined, hyperreflective foci localized typically in the outer layers of the retina on the SD-OCT B-scans with short section distance. OCT-A demonstrated the precursor lesions as the deep capillary plexus abnormalities in 3 eyes. Two eyes were progressed to stage 1 RAP during the follow-up period.
Diagnostic characteristics and clinical course of the precursor RAP lesions were defined in this study. The study has emphasized the necessity of the importance of the B-scans with short section distance for the diagnosis of precursor lesions and using “Eye-Tracked” mode SD-OCT during the follow-up.