Posters

Cataract surgery combined with intravitreal anti-VEGF injection in wet age-related degeneration

Poster Details

First Author: A.Karalezli TURKEY

Co Author(s):    S. Sul                             

Abstract Details



Purpose:

To evaluate the outcomes of phacoemulsification combined with ranibizumab in patients with wet age related macular degeneration (AMD).

Setting:

Department of Ophthalmmology, Muğla Sıtkı Koçman University

Methods:

The first month outcomes of 14 eyes of patients with wet AMD, who underwent phacoemulsification combined with a single dose of ranibizumab 0.5mg/0.5mL were determined. Pre and postoperative best-spectacle corrected visual acuities (BSCVA) were estimated with Snellen chart and converted to LogMAR. Pre- and postoperative central foveal thicknesses (CFTs), subfoveal choroidal thicknesses (SCTs) and existence of complications related with AMD (increase of subretinal fluid-intraretinal cysts, development of cystoid macular edema) were evaluated with optical coherence tomography (OCT).

Results:

All patients underwent uneventful cataract surgery combined with 0.5mg/0.5mL intravitreal ranibizumab injection. At first month, BSCVA significantly improved from 0.9±0.31 LogMAR to 0,32±0.27 LogMAR (p=0.001). CFT significantly decreased from 262±51µ to 205±29µ (p=0.001). SCT significanlty increased from 175±32µ to 195±40µ (p=0.003). There was detected no cystoid macular edema or subretinal fluid at the first month. However, in two patients, intraretinal cysts remained despite the regression of subretinal fluid

Conclusions:

SCT which seems to be related with post-surgical inflammation significantly increased despite ranibizumab injection. However, ranibizumab was effective in reducing the intraretinal and subretinal exudations related with active subfoveal neovascularization and controlling the post-surgical retinal inflammation. Cataract surgery combined with ranibizumab injection seemed to be safe and have favourable visual outcomes in patients with wet AMD and cataract.

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