First Author: G.Garhofer AUSTRIA
Co Author(s): P. Datlinger M. Tittl W. Geyer N. Maar L. Schmetterer
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To test a simple approach for characterizing subjective perception in patients with choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD).
This was a multicentre study in four private ophthalmology praxes including 20 patients with CNV.
Subjects were presented the original image on the affected eye and afterwards candidate images to the contralateral eye. Then the patients chose one image that most closely matched the perception on the affected eye. This was repeated with three different images representing three every day life scenes manipulated to mimic visual perception with reduced colour perception (image 1), central scotomas (image 2), and blurring with four varying sizes (image 3). The frequency of response to the forced choice questionnaire experiment for each image was recorded.
Images manipulated using a Gaussian blur filter, a brightness filter and a sinusoidal distortion filter were selected by 9, 10 and 1 patients, respectively. Size of modification was not associated with visual acuity in image 1 or image 3. In image 2, however, the size of the modification was dependent on visual acuity (p = 0.01).
The images presented in this study may be an interesting approach to communicate the disease with patients and their relatives. They may also facilitate involvement of patients in treatment decisions.