Polypoidal choroidal vasculopathy: The POLYON study, a real life study, about 50 cases

Poster Details

First Author: H.El Chehab FRANCE

Co Author(s):    C. Lagenaite   E. Agard   C. Dot                       

Abstract Details


The POLYON study is a multicentre descriptive analysis of the diagnostic and clinical approach of polypoid choroidal vasculopathy. The therapeutic management was also analyzed.


Lyon, France


This is a retrospective multicentre observational study analyzing diagnostic and therapeutic management in a series of patients with polypoidal choroidal vasculopathy (PCV). For each patient, clinical data and data from exams were collected. The treatments performed (intravitreal injection of anti-VEGF and / or Dynamic phototherapy) have already been collected. Follow-up was done up to 36 months.


The diagnosis of PCV was carried out in 50 patients, mean age 79 years, 50% had Aged Macular Degeneration and 30% had arterial hypertension. All of our patients had an initial pigment epithelium detachment on OCT, with an average height of 390um ± 247. The choroidal thickness was thicker in these patients (p = 0.048) compared to the other eye. Visual acuity remained stable throughout the follow-up, no significant difference was observed in the functional results between the 2 treatment groups (p> 0.1) and within each group between the beginning of the follow up and at the end of the study. PED decreased significantly in the IVI group (p = 0.001 to 30 months), and in the combined treatment group (p = 0.04 to 30 months).


The PCV is an entity to be known. Its diagnosis can be carried out by non-invasive examinations such as OCT. There was no superiority of combined treatment (PDT + anti-VEGF IVI on functional or anatomical results

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