Session Title: Free Paper Session 27: AMD VI
Session Date/Time: Sunday 10/09/2017 | 12:00-13:30
Paper Time: 12:48
Venue: Room 117
First Author: : I.Muftuoglu USA
Co Author(s): : M. Alam R. Gaber W. Freeman
To determine the presenting characteristics of neovascular age-related macular degeneration (AMD) patientswith long-term remission (LTR), which was defined as the absence of intraretinal (IRF), subretinal fluid (SRF), orhaemhorrage on spectral domain optical coherence tomography (SD-OCT) and absence of leakage on fluorescein angiography (FA) for longer than 6 months while on as needed anti-vascular endothelial growthfactor treatment.
The presenting characteristics of patients with long-term remission was compared to control group including 32 eyes of 28 age, gender and ethnicity matched patients without achieving long-term remission.
Eyes with LTR at presentation had significantly thinner subfoveal choroidal thickness (147 vs. 178 μm, p=0.04). There was more IRF and less SRF at the presentation in the remission group compared to the control group (59.3% IRF and 11.1% SRF in the remission group vs. 28.1% IRF and 34.4% SRF in the control group, p=0.03). Seventy-four percent of patients in long-term remission group had type 1 choroidal neovascular membrane, retinal angiomatous proliferation was the second most common CNV type with a rate of 18.5%; whereas 28 eyes had type 1 CNV (87.5%),none of the patients had RAP in the control group (p=0.036).
Presence of RAP, thinner choroidal thickness and more IRF and less SRF at the presentation were associated with long-term remission in patients receiving as-needed treatment.