Optical coherence tomography angiography features of choroidal neovascularization associated with choroidal nevus

Session Details

Session Title: Free Paper Session 25: Imaging IV

Session Date/Time: Sunday 10/09/2017 | 10:00-11:30

Paper Time: 10:48

Venue: Room 113

First Author: : F.Corvi ITALY

Co Author(s): :    M. Pellegrini   E. Say   C. Shields   G. Staurenghi                    

Abstract Details

Purpose:

To describe the imaging features of choroidal neovascularization (CNV) associated with choroidal nevus using optical coherence tomography angiography (OCT-A) imaging.

Setting:

This retrospective observational case series from patients presenting between May 2014 and April 2016 at the Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy and the Ocular Oncology Service at Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Methods:

Patients with CNV secondary to choroidal nevus underwent full imaging examination including fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICGA), spectral domain optical coherence tomography (SD-OCT), and OCT-A. The OCT-A features were analyzed and correlated with conventional angiography findings and SD-OCT.

Results:

There were 11 eyes from 11 patients (6 male and 5 female, mean age of 65±20.4 years) included in the analysis. FA and ICGA disclosed CNV in 90% and 83%, respectively. OCT-A displayed CNV network in 11 eyes (100%) and the pattern was classified as “sea-fan” in 8 (73%) and “long filamentous linear vessels” in 3 (27%) eyes. Distinct from CNV, intrinsic vasculature within the nevus was observed in 6 eyes (55%), corresponding to those with chronic retinal pigment epithelium changes.

Conclusions:

OCT-A is a useful imaging technique to disclose CNV associated with choroidal nevus. Despite the presence of intraretinal or subretinal fluid and haemhorrage, OCT-A revealed the CNV in all cases, results non inferior to ICGA. This imaging modality can be useful for analysis of long-standing nevi with related exudation.

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