The assessment of lamina cribrosa thickness in patients with central retinal vein occlusions

Session Details

Session Title: Free Paper Session 23: Vascular Diseases & Diabetic Retinopathy VI

Session Date/Time: Sunday 10/09/2017 | 08:00-09:30

Paper Time: 08:42

Venue: Room 120

First Author: : S.Demircan TURKEY

Co Author(s): :    O. Altunel   M. Atas                          

Abstract Details

Purpose:

To assess the lamina cribrosa thickness in patients with central retinal vein occlusion and to compare the flow velocity of central retinal artery and vein during the course behind the optic nerve head and lamina cribrosa with healthy subjects.

Setting:

Kayseri Training and Research hospital Department of Ophthalmology, Kayseri, Turkey

Methods:

32 eyes of 32 patients with central retinal vein occlusion and 34 eyes of 34 healthy controls were assessed in this study. Patients and healthy controls were appraised in the mean of other systemic and ocular disease. The lamina cribrosa thicknesses on optic nerve head of patients with central retinal vein occlusion and healthy controls were measured for both eyes with deep mode optic coherence tomography. The flow velocity of central retinal artery and vein at the level of lamina cribrosa and behind the optic nerve head were assessed with doppler ultrasonography for all subjects in the study.

Results:

The average ages of 32 (15 female (46.8%) 17 male (53.1%)) patients with central retinal vein occlusion and 34 (17 female (50%), 17 male (50%)) healthy controls were 67±11 and 66±10, respectively (p=0.833). There was no significant difference between two groups in the mean of systemic disease (hipertension p=0.670, diabetes mellitus p=0.519). the average lamina cribrosa thickness of effected eyes in patients with central retinal vein occlusion was 203.0 ±12.5 µm, it was 204.0±11.2 µm in uneffected eyes. There was no significant difference between two eyes (p=0.754). The lamina cribrosa thickness in healthy control group was 213.0 ±5.6 µm and it was significantly thicker compared to petients with central vein occlusion (p<0.001 and p<0.001). The maximum flow velocity in central retinel vein at the level of lamina cribrosa was 52.4±18.7 mm/sn in effected eyes of patients with central retinal vein occlusion and it was 57.2±17.5 mm/sn in uneffected eyes (p=0.287). It was 97.7±27.4 mm/sn in healthy control group and it was significantly lower in patient group (p<0.001 ve p<0.001).

Conclusions:

The lamina cribrosa thickness could be assessed with optic coherence tomography. The smaller and narrower lamina cribrosa might be a risk factor for central retinal vein occlusion. For this reason; protective cautions could be taken for subjects with thin lamina cribrosa.

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