Role of pachychoroid in CSCR and PCV

Session Details

Session Title: Free Paper Session 21: Imaging III

Session Date/Time: Sunday 10/09/2017 | 08:00-09:30

Paper Time: 09:12

Venue: Room 113

First Author: : S.Paliwal INDIA

Co Author(s): :    S. Gopi Krishnan   P. B V   N. K Yadav   A. Mohan                    

Abstract Details

Purpose:

To study the choroidal characteristics of central serous chorioretinopathy (CSCR) and polypoidal choroidal vasculopathy (PCV) with optical coherence tomography–assisted enhanced depth imaging (EDI-OCT) and identify associations with functional outcomes

Setting:

Tertiary eye care centre

Methods:

This retroprospective observational case series study consisted of patients with CSCR with OCT demonstrating presence of subretinal fluid or serous PED and patients of PCV with orange-red elevated lesions on fundus examination and characteristic polypoidal lesions seen on indocyanine angiography. Choroidal thickness was measured using enhanced-depth imaging optical coherence tomography (Spectralis, Heidelberg, Germany). Subfoveal choroidal thickness in each eye was analyzed by measurement of the vertical distance from the outer layer of RPE to the innermost scleral layer. Two nasal and temporal choroidal thicknesses measurements 1 mm and 2 mm apart from the foveal centre, were also evaluated in all eyes. Presence or absence of pachy vessels was subjectively evaluated. Both thickness and pachy vessels were confirmed by 3 independent graders

Results:

The study included 41 eyes with 26 eyes showing signs of CSCR and 15 eyes of PCV. The mean age of patients was 46.9 years (95% CI 43.7 - 50.0) in CSCR and 69.5 years (95% CI 64.5 – 74.5) in PCV. The mean subfoveal choroidal thickness was greater (p<0.001) in eyes with CSCR (379.2 µm – 95% CI 348.6 – 409.9) compared to eyes with PCV (264.9 µm – 95% CI 212.9 -316.9). Choroidal thickness at each of the other 4 points showed a similar tendency. EDI-OCT revealed enlargement of the outer choroidal vessels in 15 eyes with CSCR and 14 eyes with PCV (p=0.030). Vision was significantly better in CSCR (median 76 ETDRS letters range 35-80) versus PCV (median 70 ETDRS letters range 35-80) (p<0.001). There was no correlation between visual outcomes and choroidal thickness or pachy vessels

Conclusions:

CSCR is characterized by a increased choroidal thickness as compared to PCV whereas enlargement of underlying outer choroidal vessels was more characteristically seen in PCV as compared to CSCR. These findings however did not show an association with visual outcomes. From our study we may conclude that presence or absence of pachychoroid characteristics may not help to predict visual outcomes within a disease group.

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