Choroidal thickness in healthy eyes using swept-source optical coherence tomography: Automatic vs. manual measurement

Session Details

Session Title: Free Paper Session 21: Imaging III

Session Date/Time: Sunday 10/09/2017 | 08:00-09:30

Paper Time: 08:18

Venue: Room 113

First Author: : J.Ruiz Moreno SPAIN

Co Author(s): :    J. Ruiz-Medrano   F. Del Valle-Cebrian   M. Biarnes   J. Montero                    

Abstract Details

Purpose:

To determine the correlation between manual and automatic measuring software used to obtain the choroidal thickness (CT) profile of a healthy population using swept-source optical coherence tomography (SS-OCT).

Setting:

Department of Ophthalmology, Castilla La Mancha University. Albacete. Spain.

Methods:

Cross-sectional, non-interventional study. 276 eyes from 156 healthy subjects, with spherical equivalent (SE) between ±3D, were scanned using a SS-OCT (Topcon Corporation, Japan). A horizontal CT profile of the macula was created by manually measuring the subfoveal CT (SFCT) from the posterior edge of retinal pigment epithelium (RPE) to the choroid/sclera junction. Three further determinations were performed at successive points 1000 μm nasal to the fovea and five more temporal to the fovea. Then the same measures were taken automatically with software Topcon OCT DRI 9.30. The subjects were divided into five groups according to age. The mean age was 33.5±24.9 years (from 3 to 95). The mean SE was 0.11±1.36 D (range, -3.00 to +3.00).

Results:

Manual CT was always statistically significant superior to automatic CT in all 9 locations in the overall group and in the two younger groups. There are no differences between automatic vs. manual CT in subjects aged 40 or older in any of the 9 locations. The 21 to 40 years old group shows no statistically significant differences at SFCT and temporal locations when comparing both techniques, but nasal locations show statistically thicker choroids when measured manually. Correlation study showed a low correlation between manual and automatic measures. Gender, eye and SE showed no influence on the differences obtained between manual and automatic measurements in bivariate or multivariate analysis. Age in categories and location of measurement were statistically associated with differences between manual and automatic in bivariate analysis and on multivariate analysis.

Conclusions:

Automatic measuring software can be used to obtain the CT profile of a healthy population using SS-OCT, in patients aged 40 or older. In younger people, manual segmentation must be done, since automatic segmentation offers lower values.

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