Comparison of photodynamic therapy and navigated microsecond laser for chronic central serous chorioretinopathy

Session Details

Session Title: Free Paper Session 18: New Drug & Treatment Technology

Session Date/Time: Saturday 09/09/2017 | 14:30-16:00

Paper Time: 14:36

Venue: Room 120

First Author: : J.Chhablani INDIA

Co Author(s): :    C. Ntomoka   M. Gachago   H. Peguda                       

Abstract Details

Purpose:

To compare the visual and anatomical outcomes after photodynamic therapy (PDT) and navigated microsecond laser (nMSL) for chronic central serous chorioretinopathy (CSCR)

Setting:

Tertiary eye care centre

Methods:

This retrospective included eyes with chronic CSCR who underwent either PDT or nMSL with a minimum of 6 months follow up. Eyes with a history of treatment with any other modalities in the past or during 6 months follow up after PDT or microsecond laser were excluded. Primary outcome measures included change in best-corrected visual acuity (BCVA) and central macular thickness (CMT). Secondary outcome measures included changes in subretinal fluid, hyperreflective foci, cystic spaces, subfoveal choroidal thickness, outer retinal structure integrity.

Results:

Forty–five eyes of 39 subjects (PDT group – 23 eyes, nMSL group – 22 eyes) with chronic CSCR were analyzed. At six months follow up, the nMSL group had significantly higher improvement in BCVA compared to the PDT group (0.12 ± 0.24 vs -0.02 ± 0.20 (p= 0.039)). Central macular thickness (CMT) was significantly reduced in nMSL group compared to the PDT (85.5 ± 93.26 vs 24.47 ± 73.18 microns (p= 0.02)). Thirteen (59%) eyes in nMSL group had complete resolution of the SRF at 6 months compared to 5 (21.7% ) eyes in PDT group. There was no significant difference in rest of the anatomical features between the groups.

Conclusions:

Navigated microsecond laser seem to be superior over PDT in improving visual and anatomical outcomes. Subthreshold microsecond laser is a cost effective, less destructive with less potential adverse effects , therefore, it can be considered as an cheap alternative to PDT in treatment of CSCR.

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