Comparison of photodynamic therapy and navigated microsecond laser for chronic central serous chorioretinopathy

Session Details

Session Title: Free Paper Session 18: New Drug & Treatment Technology

Session Date/Time: Saturday 09/09/2017 | 14:30-16:00

Paper Time: 14:36

Venue: Room 120

First Author: : J.Chhablani INDIA

Co Author(s): :    C. Ntomoka   M. Gachago   H. Peguda                       

Abstract Details


To compare the visual and anatomical outcomes after photodynamic therapy (PDT) and navigated microsecond laser (nMSL) for chronic central serous chorioretinopathy (CSCR)


Tertiary eye care centre


This retrospective included eyes with chronic CSCR who underwent either PDT or nMSL with a minimum of 6 months follow up. Eyes with a history of treatment with any other modalities in the past or during 6 months follow up after PDT or microsecond laser were excluded. Primary outcome measures included change in best-corrected visual acuity (BCVA) and central macular thickness (CMT). Secondary outcome measures included changes in subretinal fluid, hyperreflective foci, cystic spaces, subfoveal choroidal thickness, outer retinal structure integrity.


Forty–five eyes of 39 subjects (PDT group – 23 eyes, nMSL group – 22 eyes) with chronic CSCR were analyzed. At six months follow up, the nMSL group had significantly higher improvement in BCVA compared to the PDT group (0.12 ± 0.24 vs -0.02 ± 0.20 (p= 0.039)). Central macular thickness (CMT) was significantly reduced in nMSL group compared to the PDT (85.5 ± 93.26 vs 24.47 ± 73.18 microns (p= 0.02)). Thirteen (59%) eyes in nMSL group had complete resolution of the SRF at 6 months compared to 5 (21.7% ) eyes in PDT group. There was no significant difference in rest of the anatomical features between the groups.


Navigated microsecond laser seem to be superior over PDT in improving visual and anatomical outcomes. Subthreshold microsecond laser is a cost effective, less destructive with less potential adverse effects , therefore, it can be considered as an cheap alternative to PDT in treatment of CSCR.

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