The bilaterality of polypoidal choroidal vasculopathy: Multimodality imaging

Session Details

Session Title: Free Paper Session 14: AMD IV

Session Date/Time: Friday 08/09/2017 | 16:30-18:00

Paper Time: 16:42

Venue: Room 111

First Author: : R.Hua CHINA

Co Author(s): :                                 

Abstract Details

Purpose:

To investigate the bilaterality of polypoidal choroidal vasculopathy (PCV) in Asian population, using multimodality imaging technique.

Setting:

Retrospective case series study.

Methods:

Diagnostic indocyanine green angiography (ICGA) and spectrum domain optical coherence tomography (SD-OCT) were performed to enrol the eligible PCV eye as study eye and its contralateral eye as fellow eye correspondingly.

Results:

Among 57 patients at baseline, 17.5% of PCV polyps were detected by OCT directly, Concerning the subfoveal choroidal thickness, the study eyes (269 [141-704] μm) was comparable to the fellow eyes (263 [161-688] μm) statistically (p=0.091). Moreover, no significant difference was observed in hyperfluorescent spots on ICGA between study eyes (84.2%) and fellow eyes (77.2%, p=0.342). On the contrary, the proportion of branching vascular network (BVN) and choroidal hyperpermeability on ICGA, retinal pigment epithelium detachment and double-layer sign on OCT in study eyes, was 89.5%, 68.4%, 94.7%, and 94.7%, thus significantly greater than in fellow eyes. In particular, two silent BVN without any leakage on both fluorescein angiography and ICGA were found in the fellow eyes.

Conclusions:

The results indicate that the early signs of PCV in the fellow eyes were found with similar choroidal thickness on SD-OCT, hyperfluorescent dots during ICGA, compared with the PCV eyes. Furthermore, silent BVN may be secondary to pachychoroid spectrum disorders. However, whether PCV is a binocular disease or not still needs further follow up and investigation.

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