Predictive factors for proliferative vitreoretinopathy formation after uncomplicated primary retinal detachment repair

Session Details

Session Title: Free Paper Session 13: Vitreoretinal Surgery IV

Session Date/Time: Friday 08/09/2017 | 14:30-16:00

Paper Time: 14:30

Venue: Room 117

First Author: : K.Xu CANADA

Co Author(s): :    E. Chin   D. Parke III   D. Almeida                       

Abstract Details

Purpose:

To determine predictive factors of proliferative vitreoretinopathy (PVR) formation after uncomplicated primary retinal detachment (RD) repair.

Setting:

A multi-site single private practice institution

Methods:

Retrospective single-centre case-control study of 74 consecutive patients with (37 eyes) and without (37 eyes) PVR formation after undergoing uncomplicated primary surgery for RD repair. Logistic regression was used to assess factors associated with PVR formation.

Results:

RD involving the macula was 4.2 times (adjusted odds ratio, AOR; 95% confidence interval, CI, 1.4 -12.9, p = 0.0119) more likely to have PVR formation compared to those without. Patients who were current or former smokers were 3.6 times (AOR, 95% CI: 1.1 - 11.7, p = 0.0352) more likely to have PVR formation compared to non-smokers. Compared to 25 gauge (g) vitrectomy, larger gauge vitrectomy (20-g or 23-g) was 3.6 times (AOR, 95% CI: 1.2- 11.3, p = 0.0276) more likely to have PVR formation. Duration of RD symptoms, high myopia, lens status, lattice degeneration, location of retinal break, number of retinal breaks, and surgical technique (e.g. scleral buckle with or without vitrectomy versus vitrectomy alone) were not predictive of PVR formation.

Conclusions:

Cigarette smoking, macular involvement, and large-gauge vitrectomy are significant risk factors predictive of PVR formation after uncomplicated primary RD repair.

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