Postoperative endophthalmitis in a United Kingdom region in the last 10 years

Session Details

Session Title: Free Paper Session 8: Vitreoretinal Surgery III

Session Date/Time: Friday 08/09/2017 | 08:00-09:30

Paper Time: 08:36

Venue: Room 111

First Author: : A.Shalaby UK

Co Author(s): :    S. Di Simplicio   R. Newsom   A. Lockwood                       

Abstract Details


To investigate the incidence, procedures performed, isolated causative microorganisms if found and final visual outcome of postoperative endophthalmitis in a UK tertiary referral centre.


Southampton Eye Unit


The eye unit at the Southampton University Hospitals (UK) has an electronic database that records diagnosis and treatment offered to all patient seen or admitted to the unit. This database used to carry out a retrospective audit of incidence, preceding ophthalmic procedure, vitreous biopsy culture results, management plan and visual acuity before and after treatment of all cases diagnosed with postoperative endophthalmitis in the last 10 years in the unit.


Forty patients have been diagnosed with postoperative Endophthalmitis over the audit period. 19 patients have received intravitreal antibiotics injections only (Abx IVI group) while 21 patients were treated by pars plana vitrectomy together with intravitreal antibiotics injection (PPV group). Visual outcome was recorded, compared between both groups and statistically analysed using Exact Fisher test. Our parameter was improvement of visual acuity (VA) compared to time of presentation with endophthalmitis. Statistical analysis using Exact Fisher test revealed p value=0.472731 i.e. not significant between the 2 groups. Further analysis revealed that 25 patient presented with VA of counting finger (CF) at 30 cm or worse. Out of these 25 patients; there were 12 patients treated with intravitreal antibiotics only (Abx IVI group) and 13 patients treated with pars plana vitrectomy (PPV group). There was significant difference between the two groups in terms of the visual outcome compared to their visual acuity at the time of presentation. Statistical analysis using Exact Fisher test revealed p value=0.030206 i.e. significant result.


The incidence of endophthalmitis in this audit is comparable to larger studies, suggesting that accepted benchmarks reflect UK practice Vitrectomy may be recommended for postoperative endophthalmitis patients with visual acuity of CF or worse.

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