Reduced foveal avascular zone in children with history of retinopathy of prematurity

Session Details

Session Title: Free Paper Session 7: Vascular Diseases & Diabetic Retinopathy II

Session Date/Time: Thursday 07/09/2017 | 14:30-16:00

Paper Time: 15:30

Venue: Room 117

First Author: : M.Stopa POLAND

Co Author(s): :    J. Szczapa   A. Gotz-Wieckowska   P. Rakowicz   M. Pawlak                    

Abstract Details


To compare foveal parameters measured by optical coherence tomography angiography in children who had been born preterm with healthy controls


Clinical Eye Unit and paediatric Ophthalmology Service, Heliodor Swiecicki University Hospital, Poznan University of Medical Sciences, Poznan, Poland


: a comparative case series that included 20 eyes of 11 children with a history of retinopathy of prematurity and 27 eyes of 15 healthy controls. Optical coherence tomography angiography with a scan size of 3 x 3 was performed for all eyes. Foveal avascular zone area was measured using the Optovue RTVue AVANTI instrument (Optovue Inc, Fremont, CA) software


Foveal avascular zone (FAZ) was absent in 60% (12/20) of eyes in superficial plexus and in deep plexus in the preterm born group. The mean birth weight was 877±128 g, and mean gestational age was 25.9±0.3 weeks. In contrast, FAZ was absent in 3.7% (1/27) in both plexuses in the control group. This group included children with mean birth weight of 3532±294 g, and mean gestational age 38.7±1.2 weeks.


An absent foveal avascular zone at superficial and deep level is present in more than a half of the patients with the history of ROP. Presumably higher VEGF levels after birth promoted abnormal vascularization of the fovea in these children.

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