Reduced foveal avascular zone in children with history of retinopathy of prematurity

Session Details

Session Title: Free Paper Session 7: Vascular Diseases & Diabetic Retinopathy II

Session Date/Time: Thursday 07/09/2017 | 14:30-16:00

Paper Time: 15:30

Venue: Room 117

First Author: : M.Stopa POLAND

Co Author(s): :    J. Szczapa   A. Gotz-Wieckowska   P. Rakowicz   M. Pawlak                    

Abstract Details

Purpose:

To compare foveal parameters measured by optical coherence tomography angiography in children who had been born preterm with healthy controls

Setting:

Clinical Eye Unit and paediatric Ophthalmology Service, Heliodor Swiecicki University Hospital, Poznan University of Medical Sciences, Poznan, Poland

Methods:

: a comparative case series that included 20 eyes of 11 children with a history of retinopathy of prematurity and 27 eyes of 15 healthy controls. Optical coherence tomography angiography with a scan size of 3 x 3 was performed for all eyes. Foveal avascular zone area was measured using the Optovue RTVue AVANTI instrument (Optovue Inc, Fremont, CA) software

Results:

Foveal avascular zone (FAZ) was absent in 60% (12/20) of eyes in superficial plexus and in deep plexus in the preterm born group. The mean birth weight was 877±128 g, and mean gestational age was 25.9±0.3 weeks. In contrast, FAZ was absent in 3.7% (1/27) in both plexuses in the control group. This group included children with mean birth weight of 3532±294 g, and mean gestational age 38.7±1.2 weeks.

Conclusions:

An absent foveal avascular zone at superficial and deep level is present in more than a half of the patients with the history of ROP. Presumably higher VEGF levels after birth promoted abnormal vascularization of the fovea in these children.

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