Macular thickness and volume measured by optical coherence tomography in Type 2 diabetic patients without retinopathy

Session Details

Session Title: Free Paper Session 7: Vascular Diseases & Diabetic Retinopathy II

Session Date/Time: Thursday 07/09/2017 | 14:30-16:00

Paper Time: 15:00

Venue: Room 117

First Author: : F.Ünal TURKEY

Co Author(s): :    E. Ciloglu                             

Abstract Details

Purpose:

To assess the relationship between level of HbA1c, central subfield thickness , central subfield volume and total macular volume according to duration of diabetes.

Setting:

This study is a prospective, case-control study. The study is conducted with the diabetic patients without retinopathy who were examined between June 2016-October 2016 at Ophthalmology department in Adana Numune Training and Research hospital.

Methods:

82 patients enrolled into study. The patients divided into three groups based on the duration of diabetes (<5 years , 6-10 years, >10 years). Glycosylated haemoglobin (HbA1c) was run on all patients. We measured central subfield thickness, central subfield volume, total macular volume using optic coherence tomography in all participants with diabetes mellitus without retinopathy and 82 non-diabetic controls.

Results:

The mean CST was 203±80.6 µm, the mean CSV was 0.172±0.07mm3, mean TMV was 6.428±0.30mm3 in the study group and 182±16 µm, 0.133±0.05 mm3, 6.032±0.12mm 3 respectively in the control group. The difference was statisticially significant.( p<0,001). HbA1c was 7.73±1.95 in the first group, 7.92±2.05 in the second group and 9.34±2.09 in the third group. Statistically significant relationship between HbA1c and duration of diabetes was detected. (p=0.006). According to the duration of diabetes, mean CST was 190±30.60 µm, mean CSV was 0.162±0.015 mm3 and mean TMV was 6.124±0.318mm 3 in the first group. In the second group mean CST was 196±20.0 µm, mean CSV was 0.170±0.02mm 3, mean TMV was 6.320±0.360 mm3. And third group , mean CST was 225±10 µm, mean CSV was 0.185±0.18 mm 3,mean TMV was 6.840±0.25mm 3 .When compared the groups between them ,there were statistically significant difference (p=0.03)

Conclusions:

: Even without macular edema, the macular thickness increases with longer duration of diabetes. Macular thickness measurements differ significantly between diabetic participants and non-diabetic controls.

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